Probing the role of intercalating protein sidechains for kink formation in DNA.

Protein binding can induce DNA kinks, which are for example important to enhance the specificity of the interaction and to facilitate the assembly of multi protein complexes. The respective proteins frequently exhibit amino acid sidechains that intercalate between the DNA base steps at the site of t...

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Bibliographic Details
Main Authors: Achim Sandmann, Heinrich Sticht
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5809078?pdf=render