Rapid Detection of Mobilized Colistin Resistance using a Nucleic Acid Based Lab-on-a-Chip Diagnostic System

Abstract The increasing prevalence of antimicrobial resistance is a serious threat to global public health. One of the most concerning trends is the rapid spread of Carbapenemase-Producing Organisms (CPO), where colistin has become the last-resort antibiotic treatment. The emergence of colistin resi...

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Bibliographic Details
Main Authors: Jesus Rodriguez-Manzano, Nicolas Moser, Kenny Malpartida-Cardenas, Ahmad Moniri, Lenka Fisarova, Ivana Pennisi, Adhiratha Boonyasiri, Elita Jauneikaite, Alireza Abdolrasouli, Jonathan A. Otter, Frances Bolt, Frances Davies, Xavier Didelot, Alison Holmes, Pantelis Georgiou
Format: Article
Language:English
Published: Nature Publishing Group 2020-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-64612-1