Biochemical characterization of human gluconokinase and the proposed metabolic impact of gluconic acid as determined by constraint based metabolic network analysis.

The metabolism of gluconate is well characterized in prokaryotes where it is known to be degraded following phosphorylation by gluconokinase. Less is known of gluconate metabolism in humans. Human gluconokinase activity was recently identified proposing questions about the metabolic role of gluconat...

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Bibliographic Details
Main Authors: Neha Rohatgi, Tine Kragh Nielsen, Sara Petersen Bjørn, Ivar Axelsson, Giuseppe Paglia, Bjørn Gunnar Voldborg, Bernhard O Palsson, Óttar Rolfsson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24896608/pdf/?tool=EBI