Influence of ascorbic acid and α-tocopherol on the autoxidation and in vitro antifungal activity of amphotericin B

Background and Purpose: Amphotericin B (AmB) is the standard treatment for systemic fungal infections; however, the formation of reactive oxygen species reduces the efficacy and stability of this molecule. The present study aimed to evaluate the effect of the combination of AmB with ascorbic acid an...

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Bibliographic Details
Main Authors: Mohammed Habib Belhachemi, Zahia Boucherit-Otmani, Kebir Boucherit, Sara Belmir
Format: Article
Language:English
Published: Mazandaran University of Medical Sciences 2021-03-01
Series:Current Medical Mycology
Subjects:
Online Access:http://cmm.mazums.ac.ir/article_127275_1df14b131413cf2f58f6bb6e42b57c71.pdf