Involvement of the persistent Na+ current in the diastolic depolarization and automaticity of the guinea pig pulmonary vein myocardium

The role of the Na+ current in the automaticity of the pulmonary vein myocardium was examined in isolated guinea pig pulmonary vein cardiomyocytes and tissue preparations. Tetrodotoxin inhibited the automaticity of pulmonary vein tissue preparations by suppressing the diastolic depolarization of the...

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Bibliographic Details
Main Authors: Masahiko Irie, Haruhito Hiiro, Shogo Hamaguchi, Iyuki Namekata, Hikaru Tanaka
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319356993