Involvement of the persistent Na+ current in the diastolic depolarization and automaticity of the guinea pig pulmonary vein myocardium
The role of the Na+ current in the automaticity of the pulmonary vein myocardium was examined in isolated guinea pig pulmonary vein cardiomyocytes and tissue preparations. Tetrodotoxin inhibited the automaticity of pulmonary vein tissue preparations by suppressing the diastolic depolarization of the...
Main Authors: | Masahiko Irie, Haruhito Hiiro, Shogo Hamaguchi, Iyuki Namekata, Hikaru Tanaka |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-09-01
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Series: | Journal of Pharmacological Sciences |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861319356993 |
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