Transcranial magnetic stimulation provides means to assess cortical plasticity and excitability in humans with fragile X syndrome and autism spectrum disorder

Transcranial magnetic stimulation provides means to assess cortical plasticity and excitability in humans with fragile X syndrome and autism spectrum disorder

Fragile X Syndrome (FXS) is the most common heritable cause of intellectual disability. In vitro electrophysiologic data from mouse models of FXS suggest that loss of Fragile X Mental Retardation Protein (FMRP) affects intracortical excitability and synaptic plasticity. Specifically, the cortex ap...

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Bibliographic Details
Main Authors: Lindsay M Oberman, Frederick Ifert-Miller, Umer Najib, Shahid Bashir, Ione Woollacott, Joseph Gonzalez-Heydrich, Jonathan Picker, Alexander Rotenberg, Alvaro Pascual-Leone
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-06-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
Fragile X Syndrome
Transcranial Magnetic Stimulation
excitability
plasticity
Autism Spectrum Disorders
paired pulse stimulation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsyn.2010.00026/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnsyn.2010.00026/full

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