Human Cerebrospinal Fluid Induces Neuronal Excitability Changes in Resected Human Neocortical and Hippocampal Brain Slices

Human Cerebrospinal Fluid Induces Neuronal Excitability Changes in Resected Human Neocortical and Hippocampal Brain Slices

Human cerebrospinal fluid (hCSF) has proven advantageous over conventional medium for culturing both rodent and human brain tissue. In addition, increased activity and synchrony, closer to the dynamic states exclusively recorded in vivo, were reported in rodent slices and cell cultures switching fro...

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Bibliographic Details
Main Authors: Jenny Wickham, Andrea Corna, Niklas Schwarz, Betül Uysal, Nikolas Layer, Jürgen B. Honegger, Thomas V. Wuttke, Henner Koch, Günther Zeck
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Neuroscience
Subjects:
human tissue
human cerebrospinal fluid
microelectrode array
CMOS-MEA
hippocampus
cortex
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00283/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2020.00283/full

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