Botulinum Neurotoxin Detection and Differentiation by Mass Spectrometry

Botulinum Neurotoxin Detection and Differentiation by Mass Spectrometry

Botulinum neurotoxins (BoNTs) are proteases that cleave specific cellular proteins essential for neurotransmitter release. Seven BoNT serotypes (A–G) exist; 4 usually cause human botulism (A, B, E, and F). We developed a rapid, mass spectrometry–based method (Endopep-MS) to detect and differentiate...

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Bibliographic Details
Main Authors: John R. Barr, Hercules Moura, Anne E. Boyer, Adrian R. Woolfitt, Suzanne R. Kalb, Antonis Pavlopoulos, Lisa G. McWilliams, Jurgen G. Schmidt, Rodolfo A. Martinez, David C. Ashley
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2005-10-01
Series:Emerging Infectious Diseases
Subjects:
bioterrorism
botulism
mass spectrometry
botulinum neurotoxin
research
Online Access:https://wwwnc.cdc.gov/eid/article/11/10/04-1279_article

Internet

https://wwwnc.cdc.gov/eid/article/11/10/04-1279_article

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