Evolutionary Mechanism of Immunological Cross-Reactivity Between Different GII.17 Variants

Evolutionary Mechanism of Immunological Cross-Reactivity Between Different GII.17 Variants

Human norovirus is regarded as the leading cause of epidemic acute gastroenteritis with GII.4 being the predominant genotype during the past decades. In the winter of 2014/2015, the GII.17 Kawasaki 2014 emerged as the predominant genotype, surpassing GII.4 in several East Asian countries. Hence, the...

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Main Authors: Yueting Zuo, Liang Xue, Junshan Gao, Yingyin Liao, Yanhui Liang, Yueting Jiang, Weicheng Cai, Zhiwei Qin, Jiale Yang, Jumei Zhang, Juan Wang, Moutong Chen, Yu Ding, Qingping Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Microbiology
Subjects:
norovirus
GII.17
capsid protein
immunogenicity
evolutionary mechanism
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.653719/full

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