A Kinetic Pump Integrated Microfluidic Plate (KIM-Plate) with High Usability for Cell Culture-Based Multiorgan Microphysiological Systems

A Kinetic Pump Integrated Microfluidic Plate (KIM-Plate) with High Usability for Cell Culture-Based Multiorgan Microphysiological Systems

Microphysiological systems (MPSs), including organ-on-a-chip (OoC), have attracted attention as a novel method for estimating the effects and side effects of drugs in drug discovery. To reproduce the dynamic in vivo environment, previous MPSs were connected to pump systems to perfuse culture medium....

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Bibliographic Details
Main Authors: Kenta Shinha, Wataru Nihei, Hiroko Nakamura, Tomomi Goto, Takumi Kawanishi, Naoki Ishida, Nao Yamazaki, Yuki Imakura, Shinji Mima, Kosuke Inamura, Hiroshi Arakawa, Masaki Nishikawa, Yukio Kato, Yasuyuki Sakai, Hiroshi Kimura
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Micromachines
Subjects:
microphysiological system (MPS)
organ-on-a-chip
kinetic pump
coculture
cell-based assay
Online Access:https://www.mdpi.com/2072-666X/12/9/1007

Internet

https://www.mdpi.com/2072-666X/12/9/1007

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