Genetic Modifiers at the Crossroads of Personalised Medicine for Haemoglobinopathies

Genetic Modifiers at the Crossroads of Personalised Medicine for Haemoglobinopathies

Haemoglobinopathies are common monogenic disorders with diverse clinical manifestations, partly attributed to the influence of modifier genes. Recent years have seen enormous growth in the amount of genetic data, instigating the need for ranking methods to identify candidate genes with strong modify...

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Bibliographic Details
Main Authors: Coralea Stephanou, Stella Tamana, Anna Minaidou, Panayiota Papasavva, Marina Kleanthous, Petros Kountouris
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Journal of Clinical Medicine
Subjects:
haemoglobinopathies
thalassaemia
sickle cell disease
gene modifiers
biomarkers
gene ranking
protein network
Online Access:https://www.mdpi.com/2077-0383/8/11/1927

Internet

https://www.mdpi.com/2077-0383/8/11/1927

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