Administration of Human MSC-Derived Extracellular Vesicles for the Treatment of Primary Sclerosing Cholangitis: Preclinical Data in MDR2 Knockout Mice

Administration of Human MSC-Derived Extracellular Vesicles for the Treatment of Primary Sclerosing Cholangitis: Preclinical Data in MDR2 Knockout Mice

Primary Sclerosing Cholangitis (PSC) is a progressive liver disease for which there is no effective medical therapy. PSC belongs to the family of immune-mediated biliary disorders and it is characterized by persistent biliary inflammation and fibrosis. Here, we explored the possibility of using extr...

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Bibliographic Details
Main Authors: Roberta Angioni, Bianca Calì, Vasanthy Vigneswara, Marika Crescenzi, Ana Merino, Ricardo Sánchez-Rodríguez, Cristina Liboni, Martin J. Hoogduijn, Philip Noel Newsome, Maurizio Muraca, Francesco Paolo Russo, Antonella Viola
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
inflammation
fibrosis
mesenchymal stromal cells
liver
therapy
Online Access:https://www.mdpi.com/1422-0067/21/22/8874

Internet

https://www.mdpi.com/1422-0067/21/22/8874

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