Animal models of chronic tympanic membrane perforation: in response to plasminogen initiates and potentiates the healing of acute and chronic tympanic membrane perforations in mice

Abstract Tympanic membrane perforations (TMP) are relatively common but are typically not treated in their acute stage, as most will heal spontaneously in 7–10 days. Those cases which fail to heal within 3 months are called chronic TMP which attract surgical intervention (e.g. myringoplasty), typica...

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Bibliographic Details
Main Authors: Allen Y Wang, Yi Shen, Jeffrey T Wang, Robert H Eikelboom, Rodney J Dilley
Format: Article
Language:English
Published: Wiley 2014-12-01
Series:Clinical and Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/2001-1326-3-5