Bioengineering an Artificial Human Blood–Brain Barrier in Rodents
Our group has recently created a novel in-vivo human brain organoid vascularized with human iPSC-derived endothelial cells. In this review article, we discuss the challenges of creating a perfused human brain organoid model in an immunosuppressed rodent host and discuss potential applications for ne...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-04-01
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Series: | Bioengineering |
Subjects: | |
Online Access: | https://www.mdpi.com/2306-5354/6/2/38 |