Bioengineering an Artificial Human Blood–Brain Barrier in Rodents

Our group has recently created a novel in-vivo human brain organoid vascularized with human iPSC-derived endothelial cells. In this review article, we discuss the challenges of creating a perfused human brain organoid model in an immunosuppressed rodent host and discuss potential applications for ne...

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Bibliographic Details
Main Authors: Kimia Kamal, Ben Waldau
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Bioengineering
Subjects:
Online Access:https://www.mdpi.com/2306-5354/6/2/38