Tegafur/gimeracil/oteracil (S-1) approved for the treatment of advanced gastric cancer in adults when given in combination with cisplatin: a review comparing it with other fluoropyrimidine-based therapies

Masao Kobayakawa, Yasushi KojimaDepartment of Gastroenterology, National Center for Global Health and Medicine, Tokyo, JapanAbstract: S-1 is a combination of three pharmacological compounds, namely tegafur, gimeracil, and oteracil potassium. Tegafur is a prodrug of 5-fluorouracil (5-FU), an oral flu...

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Bibliographic Details
Main Authors: Kobayakawa M, Kojima Y
Format: Article
Language:English
Published: Dove Medical Press 2011-11-01
Series:OncoTargets and Therapy
Online Access:http://www.dovepress.com/tegafurgimeraciloteracil-s-1-approved-for-the-treatment-of-advanced-ga-a8661