Deciphering the biology of KIR2DL3+ T lymphocytes that are associated to relapse in haploidentical HSCT

Abstract KIR are mainly expressed on NK cells and to a lesser extent on T lymphocytes. Although the KIR NK cell repertoire was well explored in haploidentical Hematopoietic Stem Cell Transplantation (HSCT), KIR T cell compartment remains to be investigated in this context. In this study, the investi...

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Bibliographic Details
Main Authors: Gaëlle David, Catherine Willem, Nolwenn Legrand, Zakia Djaoud, Pierre Mérieau, Alexandre Walencik, Thierry Guillaume, Katia Gagne, Patrice Chevallier, Christelle Retière
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-95245-7