Sleep Disturbance Induces Increased Cholesterol Level by NR1D1 Mediated CYP7A1 Inhibition

Sleep Disturbance Induces Increased Cholesterol Level by NR1D1 Mediated CYP7A1 Inhibition

Disturbed sleep is closely associated with an increased risk of metabolic diseases. However, the underlying mechanisms of circadian clock genes linking sleep and lipid profile abnormalities have not been fully elucidated. This study aimed to explore the important role of the circadian clock in regul...

Full description

Bibliographic Details
Main Authors: Chen Xing, Xin Huang, Yifan Zhang, Chongchong Zhang, Wei Wang, Lin Wu, Mengnan Ding, Min Zhang, Lun Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Genetics
Subjects:
CYP7A1
circadian clock
cholesterol
sleep disturbance
NR1D1
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.610496/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2020.610496/full

Similar Items