A genome-wide CRISPR screen identifies N-acetylglucosamine-1-phosphate transferase as a potential antiviral target for Ebola virus

A genome-wide CRISPR screen identifies N-acetylglucosamine-1-phosphate transferase as a potential antiviral target for Ebola virus

Genetic screens are important tools to identify host factors associated with viral infections. Here, Flint et al. perform a genome-wide CRISPR screen using infectious Ebola virus (EBOV) and show that the host transferase GNPTAB is required for EBOV infection and a potential target for antiviral ther...

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Bibliographic Details
Main Authors: Mike Flint, Payel Chatterjee, David L. Lin, Laura K. McMullan, Punya Shrivastava-Ranjan, Éric Bergeron, Michael K. Lo, Stephen R. Welch, Stuart T. Nichol, Andrew W. Tai, Christina F. Spiropoulou
Format: Article
Language:English
Published: Nature Publishing Group 2019-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-08135-4

Internet

https://doi.org/10.1038/s41467-018-08135-4

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