Unique catalytic activities and scaffolding of p21 activated kinase-1 in cardiovascular signaling
P21 activated kinase-1 has diverse functions in mammalian cells. Although a large number of phosphoproteins have been designated as Pak1 substrates from in vitro studies,emerging evidence has indicated that Pak1 may function as a signaling molecule through a unique molecular mechanism—scaffolding. B...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2013-09-01
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| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphar.2013.00116/full |