Metabolic engineering of the purine biosynthetic pathway in <it>Corynebacterium glutamicum</it> results in increased intracellular pool sizes of IMP and hypoxanthine
<p>Abstract</p> <p>Background</p> <p>Purine nucleotides exhibit various functions in cellular metabolism. Besides serving as building blocks for nucleic acid synthesis, they participate in signaling pathways and energy metabolism. Further, IMP and GMP represent industri...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2012-10-01
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| Series: | Microbial Cell Factories |
| Subjects: | |
| Online Access: | http://www.microbialcellfactories.com/content/11/1/138 |