Lysophosphatidic acid-RAGE axis promotes lung and mammary oncogenesis via protein kinase B and regulating tumor microenvironment

Lysophosphatidic acid-RAGE axis promotes lung and mammary oncogenesis via protein kinase B and regulating tumor microenvironment

Abstract Background Receptor for advanced glycation end products (RAGE) is a multi-ligand transmembrane receptor of the immunoglobulin superfamily. Lysophosphatidic acid (LPA) is a ligand for RAGE and is involved in physiological and pathophysiological conditions including cancer. However, RAGE-LPA...

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Bibliographic Details
Main Authors: Rashmi Ray, Nitish Jangde, Satyendra Kumar Singh, Sunita Sinha, Vivek Rai
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Cell Communication and Signaling
Subjects:
Cancer
Tumorigenesis
Metastasis
Migration
Invasion
Online Access:http://link.springer.com/article/10.1186/s12964-020-00666-y

Internet

http://link.springer.com/article/10.1186/s12964-020-00666-y

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