Treadmill Exercise Training Modulates Hepatic Cholesterol Metabolism and Circulating PCSK9 Concentration in High-Fat-Fed Mice

Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a novel biomarker of LDL clearance and a therapeutic target of cardiovascular disease. We examined the effects of aerobic exercise training in modulating PCSK9 abundance and hepatic sterol regulation in high-fat-fed C57BL/6 mice. Mice () were...

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Bibliographic Details
Main Authors: Shin Wen, Kavita S. Jadhav, David L. Williamson, Todd C. Rideout
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Journal of Lipids
Online Access:http://dx.doi.org/10.1155/2013/908048