A Novel Derivative of the Natural Product Danshensu Suppresses Inflammatory Responses to Alleviate Caerulein-Induced Acute Pancreatitis

Acute pancreatitis (AP), a common abdominal inflammatory disorder, is characterized by premature intracellular activation of digestive proteases within pancreatic acini and a consecutive systemic inflammatory response. Although the mechanism remains to be fully understood, inflammation is the main c...

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Bibliographic Details
Main Authors: Zhengnan Ren, Hongli Li, Miaoying Zhang, Yalei Zhao, Xin Fang, Xiu Li, Wei Chen, Hao Zhang, Yang Wang, Li-Long Pan, Jia Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02513/full