Frequencies of CD8 and DN MAIT Cells Among Children Diagnosed With Type 1 Diabetes Are Similar to Age-Matched Controls

Frequencies of CD8 and DN MAIT Cells Among Children Diagnosed With Type 1 Diabetes Are Similar to Age-Matched Controls

Mucosal-associated invariant T (MAIT) cells have been implicated in various forms of autoimmunity, including type 1 diabetes (T1D). Here, we tested the hypothesis that CD8 and double negative (DN) MAIT cell frequencies were altered among diagnosed T1D subjects compared to controls. To do this, we an...

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Bibliographic Details
Main Authors: Robert Z. Harms, Katie R. Ostlund, Monina Cabrera, Earline Edwards, Victoria B. Smith, Lynette M. Smith, Nora Sarvetnick
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
mucosal associated invariant T cells
type 1 diabetes
autoantibodies
vitamin D
human cytomegalovirus
interleukin 18
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.604157/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.604157/full

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