Inducible Loss of the Aryl Hydrocarbon Receptor Activates Perigonadal White Fat Respiration and Brown Fat Thermogenesis via Fibroblast Growth Factor 21

Inducible Loss of the Aryl Hydrocarbon Receptor Activates Perigonadal White Fat Respiration and Brown Fat Thermogenesis via Fibroblast Growth Factor 21

The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor highly expressed in hepatocytes. Researchers have employed global and liver-specific conditional <i>Ahr</i> knockout mouse models to characterize the physiological roles of the AHR; however, the gestational ti...

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Bibliographic Details
Main Authors: Nathaniel G. Girer, Dwayne Carter, Nisha Bhattarai, Mehnaz Mustafa, Larry Denner, Craig Porter, Cornelis J. Elferink
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:International Journal of Molecular Sciences
Subjects:
aryl hydrocarbon receptor
fibroblast growth factor 21
uncoupling protein 1
Online Access:https://www.mdpi.com/1422-0067/20/4/950

Internet

https://www.mdpi.com/1422-0067/20/4/950

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