Complement C1q activates tumor suppressor WWOX to induce apoptosis in prostate cancer cells.

Complement C1q activates tumor suppressor WWOX to induce apoptosis in prostate cancer cells.

BACKGROUND:Tissue exudates contain low levels of serum complement proteins, and their regulatory effects on prostate cancer progression are largely unknown. We examined specific serum complement components in coordinating the activation of tumor suppressors p53 and WWOX (also named FOR or WOX1) and...

Full description

Bibliographic Details
Main Authors: Qunying Hong, Chun-I Sze, Sing-Ru Lin, Ming-Hui Lee, Ruei-Yu He, Lori Schultz, Jean-Yun Chang, Shean-Jen Chen, Robert J Boackle, Li-Jin Hsu, Nan-Shan Chang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2685983?pdf=render

Internet

http://europepmc.org/articles/PMC2685983?pdf=render

Similar Items