mGluR5 positive modulators both potentiate activation and restore inhibition in NMDA receptors by PKC dependent pathway

<p>Abstract</p> <p>Background</p> <p>In order to understand the interaction between the metabotropic glutamate subtype 5 (mGluR5) and N-methyl-D-aspartate (NMDA) receptors, the influence of mGluR5 positive modulators in the inhibition of NMDA receptors by the noncompeti...

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Bibliographic Details
Main Authors: Liao Pei-Fei, Chen Hwei-Hsien, Chan Ming-Huan
Format: Article
Language:English
Published: BMC 2011-02-01
Series:Journal of Biomedical Science
Online Access:http://www.jbiomedsci.com/content/18/1/19