MiR-661 promotes tumor invasion and metastasis by directly inhibiting RB1 in non small cell lung cancer

MiR-661 promotes tumor invasion and metastasis by directly inhibiting RB1 in non small cell lung cancer

Abstract Background Aberrant microRNA expression has been implicated in metastasis of cancers. MiR-661 accelerates proliferation and invasion of breast cancer and ovarian cancer, while impedes that of glioma. Its role in non small cell lung cancer (NSCLC) and underlying mechanism are worthy elucidat...

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Bibliographic Details
Main Authors: Feiye Liu, Yanjun Cai, Xiaoxiang Rong, Jinzhang Chen, Dayong Zheng, Lu Chen, Junyi Zhang, Rongcheng Luo, Peng Zhao, Jian Ruan
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Molecular Cancer
Subjects:
miR-661
Non small cell lung cancer
RB
E2F1
Metastasis
Online Access:http://link.springer.com/article/10.1186/s12943-017-0698-4

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http://link.springer.com/article/10.1186/s12943-017-0698-4

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