Use of Patterned Collagen Coated Slides to Study Normal and Scleroderma Lung Fibroblast Migration

Abstract Systemic sclerosis (SSc) is a spreading fibrotic disease affecting the skin and internal organs. We aimed to model pathogenic fibroblast migration in SSc in order to identify enhancing factors, measure the effect of migrating cells on underlying extracellular matrix (ECM) and test possible...

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Bibliographic Details
Main Authors: Bahja Ahmed Abdi, Henry Lopez, Sarah Karrar, Elisabetta Renzoni, Athol Wells, Angela Tam, Oseme Etomi, J. Justin Hsuan, George R. Martin, Xu Shiwen, Christopher P. Denton, David Abraham, Richard Stratton
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02621-3