Adipocyte differentiation-related protein is induced by LRP1-mediated aggregated LDL internalization in human vascular smooth muscle cells and macrophages

Adipocyte differentiation-related protein is induced by LRP1-mediated aggregated LDL internalization in human vascular smooth muscle cells and macrophages

Aggregated LDL (agLDL) is internalized by LDL receptor-related protein (LRP1) in vascular smooth muscle cells (VSMCs) and human monocyte-derived macrophages (HMDMs). AgLDL is, therefore, a potent inducer of massive intracellular cholesteryl ester accumulation in lipid droplets. The adipocyte differe...

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Bibliographic Details
Main Authors: V. Llorente-Cortés, T. Royo, O. Juan-Babot, L. Badimon
Format: Article
Language:English
Published: Elsevier 2007-10-01
Series:Journal of Lipid Research
Subjects:
adipocyte differentiation-related protein
aggregated LDL
LDL receptor-related protein
adipophilin
human vascular smooth muscle cells
macrophages
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520424587

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http://www.sciencedirect.com/science/article/pii/S0022227520424587

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