Dopamine D1 receptor deletion strongly reduces neurotoxic effects of methamphetamine

Dopamine D1 receptor deletion strongly reduces neurotoxic effects of methamphetamine

Methamphetamine (METH) is a potent, highly addictive psychostimulant consumed worldwide. In humans and experimental animals, repeated exposure to this drug induces persistent neurodegenerative changes. Damage occurs primarily to dopaminergic neurons, accompanied by gliosis. The toxic effects of METH...

Full description

Bibliographic Details
Main Authors: S. Ares-Santos, N. Granado, I. Oliva, E. O'Shea, E.D. Martin, M.I. Colado, R. Moratalla
Format: Article
Language:English
Published: Elsevier 2012-02-01
Series:Neurobiology of Disease
Subjects:
Dopamine toxicity
TH
DAT
Glia
Amphetamine derivatives
Striatum
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996111003743

Internet

http://www.sciencedirect.com/science/article/pii/S0969996111003743

Similar Items