Isomer-specific regulation of metabolism and PPARγ signaling by CLA in human preadipocytes

Isomer-specific regulation of metabolism and PPARγ signaling by CLA in human preadipocytes

Trans-10,cis-12 conjugated linoleic acid (CLA) has previously been shown to be the CLA isomer responsible for CLA-induced reductions in body fat in animal models, and we have shown that this isomer, but not the cis-9,trans-11 CLA isomer, specifically decreased triglyceride (TG) accumulation in prima...

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Bibliographic Details
Main Authors: J.Mark Brown, Maria Sandberg Boysen, Søren Skov Jensen, Ron F. Morrison, Jayne Storkson, Renee Lea-Currie, Michael Pariza, Susanne Mandrup, Michael K. McIntosh
Format: Article
Language:English
Published: Elsevier 2003-07-01
Series:Journal of Lipid Research
Subjects:
conjugated linoleic acid
fatty acids
lipid metabolism
glucose metabolism
triglycerides
peroxisome proliferator-activated receptor gamma
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520310907

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http://www.sciencedirect.com/science/article/pii/S0022227520310907

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