Exome array analysis of adverse reactions to fluoropyrimidine-based therapy for gastrointestinal cancer.

Exome array analysis of adverse reactions to fluoropyrimidine-based therapy for gastrointestinal cancer.

Fluoropyrimidines, including 5-fluororacil (5FU) and its pro-drug Capecitabine, are the common treatment for colorectal, breast, neck and head cancers-either as monotherapy or in combination therapy. Adverse reactions (ADRs) to the treatment are common and often result in treatment discontinuation o...

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Bibliographic Details
Main Authors: Matthew Traylor, Jemma L Walker, Adele A Corrigan, Monica A Hernandez, Stephen J Newhouse, Amos A Folarin, Hamel Patel, Paul J Ross, Jeremy D Sanderson, James Spicer, Natalie J Prescott, Christopher G Mathew, Anthony M Marinaki, Cathryn M Lewis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5929530?pdf=render

Internet

http://europepmc.org/articles/PMC5929530?pdf=render

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