Increased efficiency of Campylobacter jejuni N-oligosaccharyltransferase PglB by structure-guided engineering

Conjugate vaccines belong to the most efficient preventive measures against life-threatening bacterial infections. Functional expression of N-oligosaccharyltransferase (N-OST) PglB of Campylobacter jejuni in Escherichia coli enables a simplified production of glycoconjugate vaccines in prokaryotic c...

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Bibliographic Details
Main Authors: Julian Ihssen, Jürgen Haas, Michael Kowarik, Luzia Wiesli, Michael Wacker, Torsten Schwede, Linda Thöny-Meyer
Format: Article
Language:English
Published: The Royal Society 2015-01-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.140227