The somatostatin 2A receptor is enriched in migrating neurons during rat and human brain development and stimulates migration and axonal outgrowth.

The neuropeptide somatostatin has been suggested to play an important role during neuronal development in addition to its established modulatory impact on neuroendocrine, motor and cognitive functions in adults. Although six somatostatin G protein-coupled receptors have been discovered, little is kn...

Full description

Bibliographic Details
Main Authors: Virginia Le Verche, Angela M Kaindl, Catherine Verney, Zsolt Csaba, Stéphane Peineau, Paul Olivier, Homa Adle-Biassette, Christophe Leterrier, Tania Vitalis, Julie Renaud, Bénédicte Dargent, Pierre Gressens, Pascal Dournaud
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2677669?pdf=render