The involvement of aggrecan polymorphism in degeneration of human intervertebral disc and articular cartilage
The functions of the intervertebral disc and of articular cartilage are intimately related to their aggrecan content. Aggrecan is a proteoglycan that interacts with hyaluronan to form large aggregates, which are responsible for the ability of the tissues to resist compressive loads. This function is...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
AO Research Institute Davos
2006-01-01
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Series: | European Cells & Materials |
Subjects: | |
Online Access: | http://www.ecmjournal.org/journal/papers/vol011/pdf/v011a01.pdf |