Bidirectional Causal Associations Between Inflammatory Bowel Disease and Ankylosing Spondylitis: A Two-Sample Mendelian Randomization Analysis

Bidirectional Causal Associations Between Inflammatory Bowel Disease and Ankylosing Spondylitis: A Two-Sample Mendelian Randomization Analysis

BackgroundAssociations between inflammatory bowel disease (IBD) [including ulcerative colitis (UC) and Crohn’s disease (CD)] and ankylosing spondylitis (AS) were discovered in observational studies, but no evidence supported the causal relationship between the two diseases.MethodsWe employed two-sam...

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Bibliographic Details
Main Authors: Zhiyong Cui, Guojin Hou, Xiangyu Meng, Hui Feng, Baichuan He, Yun Tian
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Genetics
Subjects:
ankylosing spondylitis
inflammatory bowel disease
ulcerative colitis
Crohn’s disease
Mendelian randomization
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.587876/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2020.587876/full

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