Role of TRPV1 in the Differentiation of Mouse Embryonic Stem Cells into Cardiomyocytes.

Cytosolic Ca2+ ([Ca2+]i) is an important signal that regulates cardiomyocyte differentiation during cardiogenesis. TRPV1 is a Ca2+-permeable channel that is expressed in cardiomyocytes. In the present study, we utilized mouse embryonic stem cell-derived cardiomyocytes (mESC-CMs) as a model to invest...

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Bibliographic Details
Main Authors: Yan Qi, Zenghua Qi, Zhichao Li, Chun-Kit Wong, Chun So, Iek-Chi Lo, Yu Huang, Xiaoqiang Yao, Suk-Ying Tsang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4514823?pdf=render