Identification of epigenetically altered genes in sporadic amyotrophic lateral sclerosis.

Amyotrophic lateral sclerosis (ALS) is a terminal disease involving the progressive degeneration of motor neurons within the motor cortex, brainstem and spinal cord. Most cases are sporadic (sALS) with unknown causes suggesting that the etiology of sALS may not be limited to the genotype of patients...

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Bibliographic Details
Main Authors: Claudia Figueroa-Romero, Junguk Hur, Diane E Bender, Colin E Delaney, Michael D Cataldo, Andrea L Smith, Raymond Yung, Douglas M Ruden, Brian C Callaghan, Eva L Feldman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3530456?pdf=render