Transcriptional instability during evolving sepsis may limit biomarker based risk stratification.

Sepsis causes extensive morbidity and mortality in children worldwide. Prompt recognition and timely treatment of sepsis is critical in reducing morbidity and mortality. Genomic approaches are used to discover novel pathways, therapeutic targets and biomarkers. These may facilitate diagnosis and ris...

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Bibliographic Details
Main Authors: Antonia Kwan, Mike Hubank, Asrar Rashid, Nigel Klein, Mark J Peters
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3609793?pdf=render