Neuraminidase and SIGLEC15 modulate the host defense against pulmonary aspergillosis

Neuraminidase and SIGLEC15 modulate the host defense against pulmonary aspergillosis

Summary: Influenza-associated pulmonary aspergillosis (IAPA) has been reported increasingly since the advent of use of neuraminidase (NA) inhibitors following the 2009 influenza pandemic. We hypothesize that blocking host NA modulates the immune response against Aspergillus fumigatus. We demonstrate...

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Bibliographic Details
Main Authors: Intan M.W. Dewi, Cristina Cunha, Martin Jaeger, Mark S. Gresnigt, Marina E. Gkountzinopoulou, Fadel M. Garishah, Cláudio Duarte-Oliveira, Cláudia F. Campos, Lore Vanderbeke, Agustin Resendiz Sharpe, Roger J. Brüggemann, Paul E. Verweij, Katrien Lagrou, Greetje Vande Velde, Quirijn de Mast, Leo A.B. Joosten, Mihai G. Netea, Andre J.A.M. van der Ven, Joost Wauters, Agostinho Carvalho, Frank L. van de Veerdonk
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Cell Reports Medicine
Subjects:
aspergillosis
neuraminidase
oseltamivir
SIGLEC15
Online Access:http://www.sciencedirect.com/science/article/pii/S2666379121001178

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http://www.sciencedirect.com/science/article/pii/S2666379121001178

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