Axl activation attenuates neuroinflammation by inhibiting the TLR/TRAF/NF-κB pathway after MCAO in rats

Background and purpose: Ischemic stroke activates Toll-like receptors (TLRs), triggering rapid inflammatory cytokine production. Axl signaling has multiple roles, including regulating cytokine secretion, clearing apoptotic cells, and maintaining cell survival, however, its role in inflammation after...

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Bibliographic Details
Main Authors: Guangyong Wu, Devin W. McBride, John H. Zhang
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Neurobiology of Disease
Subjects:
Axl
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996117302693