Pirfenidone prevents acute kidney injury in the rat

Abstract Background Pirfenidone is an orally active drug used for the treatment of idiopathic pulmonary fibrosis to slow loss of lung function; it acts mainly through an antifibrotic effect but also possesses antioxidant and anti-inflammatory properties. We assessed the effect of prophylactic admini...

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Bibliographic Details
Main Authors: Ixchel Lima-Posada, Francesco Fontana, Rosalba Pérez-Villalva, Nathan Berman-Parks, Norma A. Bobadilla
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Nephrology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12882-019-1364-4