<i>FUT2</i> Secretor Status Influences Susceptibility to VP4 Strain-Specific Rotavirus Infections in South African Children

Gastroenteritis is a preventable cause of morbidity and mortality worldwide. Rotavirus vaccination has significantly reduced the disease burden, but the sub-optimal vaccine efficacy observed in low-income regions needs improvement. Rotavirus VP4 ‘spike’ proteins interact with FUT2-defined, human his...

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Bibliographic Details
Main Authors: Jaime MacDonald, Michelle J. Groome, Janet Mans, Nicola Page
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/9/10/795