Replication origin location might contribute to genetic variability in Trypanosoma cruzi

Replication origin location might contribute to genetic variability in Trypanosoma cruzi

Abstract Background DNA replication in trypanosomatids operates in a uniquely challenging environment, since most of their genomes are constitutively transcribed. Trypanosoma cruzi, the etiological agent of Chagas disease, presents high variability in both chromosomes size and copy number among stra...

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Bibliographic Details
Main Authors: Christiane Bezerra de Araujo, Julia Pinheiro Chagas da Cunha, Davi Toshio Inada, Jeziel Damasceno, Alex Ranieri Jerônimo Lima, Priscila Hiraiwa, Catarina Marques, Evonnildo Gonçalves, Milton Yutaka Nishiyama-Junior, Richard McCulloch, Maria Carolina Elias
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Genomics
Subjects:
Replication origins
Trypanosoma cruzi
Genetic variability
DGF-1
Online Access:http://link.springer.com/article/10.1186/s12864-020-06803-8

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