Laminin α4 deficient mice exhibit decreased capacity for adipose tissue expansion and weight gain.

Obesity is a global epidemic that contributes to the increasing medical burdens related to type 2 diabetes, cardiovascular disease and cancer. A better understanding of the mechanisms regulating adipose tissue expansion could lead to therapeutics that eliminate or reduce obesity-associated morbidity...

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Bibliographic Details
Main Authors: Marcella K Vaicik, Jill Thyboll Kortesmaa, Sofia Movérare-Skrtic, Jarkko Kortesmaa, Raija Soininen, Göran Bergström, Claes Ohlsson, Li Yen Chong, Björn Rozell, Margo Emont, Ronald N Cohen, Eric M Brey, Karl Tryggvason
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0109854