Development of a whole organ culture model for intervertebral disc disease

Background/Objective: Whole organ in vitro intervertebral disc models have been associated with poor maintenance of cell viability. No previous studies have used a rotating wall vessel bioreactor for intervertebral disc explants culture. The purpose of this study was to develop and validate an in vi...

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Bibliographic Details
Main Authors: James T. Stannard, Kazuya Edamura, Aaron M. Stoker, Grace D. O'Connell, Keiichi Kuroki, Clark T. Hung, Theodore J. Choma, James L. Cook
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:Journal of Orthopaedic Translation
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X15000595