Foxc1 dependent mesenchymal signalling drives embryonic cerebellar growth

Foxc1 dependent mesenchymal signalling drives embryonic cerebellar growth

Loss of Foxc1 is associated with Dandy-Walker malformation, the most common human cerebellar malformation characterized by cerebellar hypoplasia and an enlarged posterior fossa and fourth ventricle. Although expressed in the mouse posterior fossa mesenchyme, loss of Foxc1 non-autonomously induces a...

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Bibliographic Details
Main Authors: Parthiv Haldipur, Gwendolyn S Gillies, Olivia K Janson, Victor V Chizhikov, Divakar S Mithal, Richard J Miller, Kathleen J Millen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-12-01
Series:eLife
Subjects:
neurodevelopmental disorder
radial glia
cerebellum
Cxcl12
foxc1
Online Access:https://elifesciences.org/articles/03962

Internet

https://elifesciences.org/articles/03962

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