Cross-Species Antiviral Activity of Goose Interferons against Duck Plague Virus Is Related to Its Positive Self-Feedback Regulation and Subsequent Interferon Stimulated Genes Induction

Cross-Species Antiviral Activity of Goose Interferons against Duck Plague Virus Is Related to Its Positive Self-Feedback Regulation and Subsequent Interferon Stimulated Genes Induction

Interferons are a group of antiviral cytokines acting as the first line of defense in the antiviral immunity. Here, we describe the antiviral activity of goose type I interferon (IFNα) and type II interferon (IFNγ) against duck plague virus (DPV). Recombinant goose IFNα and IFNγ proteins of approxim...

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Bibliographic Details
Main Authors: Hao Zhou, Shun Chen, Qin Zhou, Yunan Wei, Mingshu Wang, Renyong Jia, Dekang Zhu, Mafeng Liu, Fei Liu, Qiao Yang, Ying Wu, Kunfeng Sun, Xiaoyue Chen, Anchun Cheng
Format: Article
Language:English
Published: MDPI AG 2016-07-01
Series:Viruses
Subjects:
goose interferon
duck plague virus
feedback regulation
antiviral activity
interferon stimulated gene
Online Access:http://www.mdpi.com/1999-4915/8/7/195

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http://www.mdpi.com/1999-4915/8/7/195

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